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Asbestos Stopped the Clock

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Asbestos in LSU clock tower
LSU Clock Tower

After almost a hundred years of service, the Louisiana State University (LSU) Memorial Tower in Baton Rouge was ready for restoration, but asbestos stopped the clock tower project when the potentially deadly mineral was found in the interior.

History

The tower was built in the early 1920s in memory of 1,447 Louisiana soldiers who died in World War I. The interior of the tower houses a military museum.

The Memorial Tower clock holds a special place in the heart of students and the community for its chimes. The bells ring every quarter hour until 10 pm and at noon they ring the tune of the university’s alma mater song. On Valentine’s Day, tradition states that receiving a kiss under the tower at the ringing of the chimes at midnight – the only night they ring past 10 pm – confirms a student is now an “official” LSU student.

The 175’ tall building was designed in the Italian Renaissance style and is a landmark in the city.

From its history, it is evident the tower is an important part of Louisiana’s past – from its construction in 1923, to today, and into the future. The restoration will ensure the building and its traditions carry on for future generations of students.

The restoration

Finding asbestos was not completely unexpected, as many buildings in the United States were built using the mineral from the 1920s until the late 1970s. Until renovations began, the asbestos was undisturbed and therefore not a danger. But once substances containing asbestos are handled, fibers can become airborne and inhaled by workers or others who are in the affected area.

When found in the tower, work on the interior was stopped and tests are currently underway. Most other buildings on the LSU campus were also constructed during this time period, meaning that as they are restored, they may also need testing and possibly abatement.

Because the asbestos was discovered at the beginning of the restoration, the university states there is no threat to students or faculty members. As a precaution, remodeling or renovations performed on any commercial buildings, schools, or residences during the time period asbestos was commonly used in construction, may require testing on possible asbestos-laden products before initiating a project.

Exposure to asbestos is a known cause of cancers, such as lung cancer and mesothelioma. At this time, mesothelioma remains a fatal disease. Mesothelioma can go undetected for decades – even 50 years – which makes it a silent killer. Early detection is critical.

Asbestos stopped the clock, but it will chime again

Exterior renovations continue and the entire $6.8 million project should be completed by the 2020 Fall semester. Baton Rouge, especially LSU students and alumni, look forward to enjoying their celebrated clock tower once again.

Photo by: Kkmurray – Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=2666826

 

Should a Mesothelioma Patient Receive the Flu Vaccine

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Since there are conflicting opinions on getting the flu vaccine, should a mesothelioma patient receive the flu vaccine? These patients in particular, along with the elderly, young children, and people living with some chronic health issues, should assess the pros and cons of receiving the vaccine.

What do the experts say?

According to the Centers for Disease Control and Prevention (CDC), flu vaccines given with a needle cannot cause the flu. Even the vaccine given through a nasal spray, though it has a live virus, has been weakened and cold-adapted so it cannot infect a person as it would not survive the body’s warmth. Because there are a number of vaccines available, anyone with health problems should confer with their doctor to receive the correct one.

The CDC strongly encourages everyone to get the vaccine since flu is a serious, and sometimes deadly, disease. The risk of not getting the vaccine is greater than receiving it.

Currently, that means a shot or nasal spray every year as the virus is seasonal. Fortunately, there is a new type of vaccine on the horizon that may mean a vaccine only every few years.

The Universal Flu Vaccine

For decades, scientists searched for a universal vaccine that could eliminate the yearly shot and cover a variety of flu viruses. This is important, not only for patient convenience, but seasonal vaccine development means scientists have to guess what virus may be prevalent in any one year. A universal vaccine could eliminate that problem.

Currently, there are numerous vaccines in various stages of development. The one currently closest to release is the M-001 by BiondVax Pharmaceuticals Ltd. The company has recently enrolled its final participant so it can begin a Phase 3 trial.

Tamar Ben-Yedidia, the chief scientific officer at BiondVax, stated, “A universal flu vaccine is often referred to as “’The Holy Grail’ of influenza research, and like the Holy Grail, it is challenging to achieve.” He also said in a press release, “This challenging trial aims to show the extent to which M-001 protects people against influenza illness, regardless of the flu strain.” The M-001 vaccine is free of all viruses, but instead contains nine viral epitopes – the antibody binding sites on an antigen – which are recognized by the immune system.

Though the M-001 is currently furthest along in trials, all the flu vaccines use similar strategies. They target the least variable parts of the flu virus to produce immunity.

Why Should a Mesothelioma Patient Receive the Flu Vaccine?

As expressed by the CDC, a person with already weakened systems, such as the lungs, is more at risk of harm by getting the flu rather than getting a vaccine. Not only should the mesothelioma victim be vaccinated, but all those people normally around them.

Since a universal vaccine will mean a more successful and targeted answer to various flu viruses, chances of actually contracting the flu will be less. Those with mesothelioma already fight a serious disease and anything they can do to stay healthy will assist in that fight. This universal flu vaccine is one more tool to prolong life and ease the pain and discomfort of this detestable disease.

New Test for Cancer Diagnoses Shows Promise

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Currently, tests to determine if there are cancer cells in a person take at least a week before getting results, but a new test for cancer diagnoses shows promise with results seen in ten minutes.

What is this test?

This test is based on a discovery by researchers at the University of Queensland’s Australian Institute for Bioengineering and Nanotechnology (AIBN). What they discovered is a one-of-a-kind DNA signature that seems to be common to all types of cancer. They found this unique DNA in intense clusters of methyl groups in certain locations.

One of the researchers at AIBN, Professor Matt Trau, explained, “Virtually every piece of cancerous DNA we examined had this highly predictable pattern. It seems to be a general feature for all cancer. It’s a startling discovery.” This discovery was followed by another showing that when these methyl clusters are inserted into a solution, the cancer DNA pieces fold into 3-dimensional nanostructures and, at that point, can stick to gold.

Once researchers found this, they created a test using gold nanoparticles that change color if 3D nanostructures of cancer DNA are present. “This happens in one drop of fluid. You can detect it by eye, it’s as simple as that,” revealed Professor Trau. This is basically the same technology as using strip indicators to test for pregnancy.

Cancer diagnoses benefits found so far:

• Works on all types of cancers tested to date
• Simple – no complicated and expensive lab equipment needed
• Fast – results in 10 minutes
• Portable – eventually could test via mobile phone
• Accuracy – as high as 90% in some cancers

Is there a downside?

This test is new. It is not perfect. Will it give too many false positive diagnoses? Does it truly identify all types of cancer – or were researchers just fortunate in which ones were tested? Only time will tell, but the future appears to be very promising.

What is the future?

This technology was tested on 200 samples using cells from various types of cancers as well as healthy cells, but a great deal more testing is needed before this is generally accepted and available.

The simplicity and affordability of this test could mean life or death for many. Researchers tested their discovery on multiple types of breast cancer, colorectal cancer, prostate cancer, and lymphoma – all with good results. Hopefully it will soon be tested on asbestos lung cancer and mesothelioma as a quick diagnosis could accelerate treatment.

Dr. Abu Sina, an AIBN researcher, said, ”It works for tissue derived genomic DNA and blood derived circulating free DNA. This new discovery could be a game-changer in the field of point of care cancer diagnostics.” That is the hope for all and a research worth watching.

Veterans Day is a National Thank You to All Who Served

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While Veterans Day began as “a day to be dedicated to the cause of world peace and to be thereafter celebrated and known as ‘Armistice Day’,” we now set aside November 11th as a time to honor our military men and women as a national thank you to all who served and are serving our country.

The history

1919

Armistice Day was proclaimed by President Woodrow Wilson in a message one year after the end of World War I. In it he stated, “To us in America the reflection of Armistice Day will be filled with solemn pride in the heroism of those who died in the country’s service, and with gratitude for the victory, both because of the thing from which it has freed us and because of the opportunity it has given America to show her sympathy with peace and justice in the councils of nations.”

1924

In June, 1924, Congress requested a resolution from President Calvin Coolidge to deliver an annual proclamation for the observance of November 11th with “appropriate ceremonies.”

1938

Congress approved an Act on May 13, 1938 making each November 11th a legal holiday, “dedicated to the cause of world peace and to be thereafter celebrated and known as ‘Armistice Day’.”

1945

In 1945, Raymond Weeks, a World War II veteran from Birmingham, Alabama, determined all veterans, not just those who served in WWI, should be celebrated. He led a delegation to Gen. Dwight Eisenhower, who also supported the idea of a national Veterans Day. In many ways, Mr. Weeks is the “Father of Veterans Day” as we know it today.

1947

The first national celebration was held in Alabama and led by Mr. Weeks.

1954

On May 26, 1954, President Eisenhower signed a bill establishing Armistice Day as a national holiday. Just a week later, Congress amended the new law by changing the name from Armistice Day to Veterans Day.

1971

In accordance with the Uniform Monday Holiday Act, Veterans Day was moved to the fourth Monday of October. However, seven years later it was returned to November 11th, but celebrated on either Friday or Monday if it occurs on the weekend.

How can we say thank you to all who served?

Many who served, especially those on ships, were exposed to asbestos in addition to the dangers of their service. From WWII through Vietnam, veterans faced this unseen danger. Many ships continued in service long after Vietnam. In fact, of the almost 3,000 Americans diagnosed with malignant mesothelioma annually, a significant percentage of them served in the U.S. Navy.

Though the asbestos fibers were unseen, they were throughout the ships: fireproofing, steam lines, pumps, boilers, condensers, evaporators, distillers, turbines, deck material, and electrical equipment.

Since there can be 50 years between exposure and diagnosis, service men and women still suffer from diseases brought about through exposure on ships. In those same years, those at home were also exposed through building materials or other occupations.

Banning asbestos in the United States is long overdue. Let your voice be heard by contacting the EPA and letting them know you want a ban. There is no safe level of exposure. While we can’t turn back the clock for our military men and women who suffered exposure, we can say “thank you” by working to prevent exposure to their children and grandchildren. Click here to find out how you can be heard.

Studies Continue in Search of a Mesothelioma Cure

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Mesothelioma is a disease primarily caused by asbestos exposure and is usually fatal within a short period of time, however studies continue in search of a mesothelioma cure. This is not a simple task, as researchers are still not sure of the reason asbestos fibers encourage cancer in some individuals. With the long latency period between exposure and diagnosis, people will be fighting this disease for many decades to come. That means that new treatments to defeat the disease are urgently needed.

In the past, and currently, treatments often consisted of chemotherapy, radiation therapy, or surgery. These have extended the lives of many patients and they still do. However, as noted by the American Cancer Society, there are new studies and treatments that carry the promise that they may do more than extend life for a few months and actually bring about a cure.

What are the latest treatments?

While there are treatments currently in use, they are often limited in their effect and generally extend life a little longer rather than cure the disease. New ideas and studies take place all the time. Some of the newest treatments still under testing are listed below.

Immunotherapy

Clinical trials are underway using a patient’s own immune cells to attack their cancer. These cells are removed from the blood, taken to the lab where they are manipulated to react to tumor cells. They are then put back into the patient’s body through a blood transfusion. The presumption is these transformed immune cells will encourage the patient’s immune system to kill the cancer cells.

One other immunotherapy in trials uses tremelimumab, a drug that encourages the immune system to attack full force as it targets specific immune cells.

Gene therapy

This innovative treatment uses modified viruses and injects them into the cancer cells. Once an infection is created, the virus introduces new selected genes into the cells, which makes the cells easier to destroy. In some tests, the gene present in the virus assists in turning on the immune system to attack the cancer cells.

Virus therapies

Still in the early stages of testing, a specially created virus is put into the pleural space of the cancer cell. In the desired outcome, the virus would directly infect and then kill the cancer cells, or indirectly, the immune system would be encouraged to kill the cancer cells.

Targeted drugs

While chemotherapy has been used for some time but with limited success, there are newer chemotherapy drugs in tests that may do much more. These drugs are targeted to a specific type of cell or protein instead of standard chemotherapy that affects the whole body. This means there are usually fewer side effects.

Photodynamic therapy

While it sounds futuristic, there are a number of clinical trials in process that study the use of photodynamic therapy (PDT). Veins are injected with a light-activated drug. Once in the body, it spreads into cancer cells throughout the body. After a few days, a tube with a special red light on the tip is placed into the chest, usually after a surgery. The drug is activated by the light producing a chemical change that kills the cancer cells. Because all this happens only within the cancer cells, there may be fewer side effects.

Encouraging progress

The knowledge that studies continue in search of a mesothelioma cure should be an encouragement to anyone diagnosed with the disease or who have a experienced extended exposure to asbestos. Contact your doctor or this link to view current trials and, perhaps, find a new trial that interests you. There is hope, and we need to support those who are researching for ways to combat and kill mesothelioma before it continues its deadly toll.