Mesothelioma Asbestos Lawyer, DuBose Law Firm, PLLC

Main navigation

You are here: Home / Archives for Asbestos / Cancer

Cancer

New Test for Cancer Diagnoses Shows Promise

By

Currently, tests to determine if there are cancer cells in a person take at least a week before getting results, but a new test for cancer diagnoses shows promise with results seen in ten minutes.

What is this test?

This test is based on a discovery by researchers at the University of Queensland’s Australian Institute for Bioengineering and Nanotechnology (AIBN). What they discovered is a one-of-a-kind DNA signature that seems to be common to all types of cancer. They found this unique DNA in intense clusters of methyl groups in certain locations.

One of the researchers at AIBN, Professor Matt Trau, explained, “Virtually every piece of cancerous DNA we examined had this highly predictable pattern. It seems to be a general feature for all cancer. It’s a startling discovery.” This discovery was followed by another showing that when these methyl clusters are inserted into a solution, the cancer DNA pieces fold into 3-dimensional nanostructures and, at that point, can stick to gold.

Once researchers found this, they created a test using gold nanoparticles that change color if 3D nanostructures of cancer DNA are present. “This happens in one drop of fluid. You can detect it by eye, it’s as simple as that,” revealed Professor Trau. This is basically the same technology as using strip indicators to test for pregnancy.

Cancer diagnoses benefits found so far:

• Works on all types of cancers tested to date
• Simple – no complicated and expensive lab equipment needed
• Fast – results in 10 minutes
• Portable – eventually could test via mobile phone
• Accuracy – as high as 90% in some cancers

Is there a downside?

This test is new. It is not perfect. Will it give too many false positive diagnoses? Does it truly identify all types of cancer – or were researchers just fortunate in which ones were tested? Only time will tell, but the future appears to be very promising.

What is the future?

This technology was tested on 200 samples using cells from various types of cancers as well as healthy cells, but a great deal more testing is needed before this is generally accepted and available.

The simplicity and affordability of this test could mean life or death for many. Researchers tested their discovery on multiple types of breast cancer, colorectal cancer, prostate cancer, and lymphoma – all with good results. Hopefully it will soon be tested on asbestos lung cancer and mesothelioma as a quick diagnosis could accelerate treatment.

Dr. Abu Sina, an AIBN researcher, said, ”It works for tissue derived genomic DNA and blood derived circulating free DNA. This new discovery could be a game-changer in the field of point of care cancer diagnostics.” That is the hope for all and a research worth watching.

On September 26th We Remember Asbestos Victims and Push Forward for a Ban

By

The Asbestos Disease Awareness Organization (ADAO) takes asbestos exposure seriously as they have heard the stories of thousands who have died, and so each year on September 26th they remember asbestos victims and push forward for a ban on this deadly mineral.

While many countries around the world have banned the use and import of asbestos, it is still legal in the United States. It is proven to be a cancer-causing substance for those exposed as there is no safe level of exposure to asbestos.

Mesothelioma Awareness Day

This year the ADAO has moved from a Mesothelioma Awareness Day on September 26th to proclaiming September a Mesothelioma Awareness Month to increase the reach to people that can be educated to the threat of asbestos use and the need for caution when working with any material that may contain asbestos.

How can we remember asbestos victims and push forward for a ban?

• Right now you can sign a petition to ban asbestos. By clicking this link, you’ll be directed to a page where you can sign. The more legislators who see the interest of citizens for a ban, the more they can push the Environmental Protection Agency (EPA) to increase the current rules, recognize the dangers, and get to the point of an outright ban.

• Join the chat on Twitter September 26th, from 12-1 PM ET. Go to #ENDMeso – for that hour, you’ll find questions about asbestos awareness as well as comments from people personally affected by asbestos exposure and mesothelioma, a deadly disease directly connected to exposure. The purpose is to create a global conversation between experts, victims, advocates, and anyone concerned about the dangers and the long delay in stopping the use of asbestos in the US.

• Light a candle on September 26th for the Mesothelioma Warriors lost to the disease and those who continue to fight for their lives.

• Participate in the 9th Annual Miles for Meso 5K Race and 3K Walk/Fun-Run. Last year $30,000 was raised to help fund awareness and education efforts. The race in in Alton, Illinois, but is available to anyone through the ADAO’s Virtual Team where you can join in from the front of your computer.

The urgency of a ban

Mesothelioma is a disease that often takes decades to appear after exposure. It currently has no cure. Because of the long lag between exposure and diagnosis, people exposed today may not develop the disease until 2050! This cycle needs to stop now and asbestos must be banned to stop it.

In addition to the steps you can take outlined above, you can donate to the ADAO as a partner in the fight for a ban. You can directly contact the EPA and your legislators. You can be an advocate for the health of many by adding your voice to stop the import and use of asbestos now.

Will Elephants Help Scientists Find a Way to Combat Human Cancers?

By

New cells going awry as they replace older cells in the body can often lead to cancer, but a study in the Cell Reports journal describes a way that elephants may lead scientists to new ways to combat human cancers.

Bigger may be better

Since cells are a critical component of acquiring cancer, it is reasonable to think that a large mammal, such as an elephant, would develop more cancers than a smaller mammal, such as a human, since it would clearly have hundreds of times more cells in its large body. However, elephants rarely get cancer in any form.

A paper published by Joshua Schiffman, a pediatric oncologist at the University of Utah, and his team, pointed out an interesting finding showing organism size and cancer rates are the reverse of what rational thought would suppose. In our bodies is a tumor-suppressing gene – P53. Whereas humans have one copy of this important gene; elephants have 20.

The purpose of P53

P53 acts as a genetic triage manager, recognizing abnormal DNA and determining whether to repair or destroy the cell. This is where elephants excel with their overload of P53. For the most part, damaged cells in elephants are killed, not repaired, while other mammals – including humans – tend to try to repair first. Since these damaged cells are killed immediately in elephants, they don’t have time to become cancerous.

Vincent Lynch, who led the study team and is an evolutionary biologist at the University of Chicago, stated, “Elephants are weird. Their cells just die if you give them DNA damage.” He wanted to know why. This quest lead to finding the answer in LIF genes.

What are LIF genes?

He found this strange phenomenon by looking for what genes might be genetically different between an elephant and other small-bodied mammals. Primarily they were looking for genes with extra copies. That’s when he found that one gene, Leukemia Inhibitory Factor, or LIF – known for enhancing fertility – also killed aberrant cells. Almost every mammal, including humans have one copy of LIF, but elephants, manatees, and the hyrax, have many. Elephants have anywhere from 7 to 11 copies. LIF6 is the only gene that appears to act as the executioner when P53 orders a cell killed and only elephants have that specific gene.

Lynch and his team confirmed their suspicions by damaging DNA from African elephant cells in the lab. This pulled the trigger for P53 to give orders to the LIF6 gene, which then killed the damaged cells. But, when LIF6 was made non-functioning, the P53 had nowhere to turn and the elephant sensitivity to cell damage no longer worked, leaving the damaged cells free to roam and multiply.

Ways to combat human cancers are just beginning

P53 and LIF6 functions in elephants are remarkable finds, but there is more to study. In fact, one ongoing study focuses on a set of genes that works to repair elephant DNA instead of killing the cells.

Researchers hope that these in-depth studies of cancer defenses in elephants will be the start of finding additional treatments for cancer in humans.

New Orleans Workers at the W.R. Grace Vermiculite Exfoliation Plant Were Exposed to Asbestos

By

New Orleans workers at the W.R. Grace vermiculite exfoliation plant were exposed to asbestos from 1965 to 1989. The facility is located in Jefferson Parish on River Road. During this time, the plant received 148,000 tons of asbestos-contaminated vermiculite from the Libby, Montana mine, also owned by W.R. Grace.

Libby, Montana

The vermiculite mine in Libby operated from the early 1920s until 1990, producing over 70% of vermiculite sold in the U.S. Though vermiculite is a naturally occurring mineral – in appearance, much like mica with multiple shiny layers – it was contaminated with asbestos in the Libby mine. W.R. Grace both mined and processed the ore and then shipped to locations all over the United States, including Louisiana.

The dangers of asbestos contaminated vermiculite

Inhalation is the primary means of exposure to asbestos. As tons of vermiculite were shipped to a location, processed, and shipped out to other locations, the ore released asbestos fibers into the air. These could also be released during the mining, milling, and exfoliation operations. Though workers were the most susceptible to exposure, people in nearby offices and residences could also be exposure, as well as their family members. In the case of W.R. Grace in New Orleans, there is a residential area a few hundred feet northeast of the site.

A report from the U.S. Department of Health and Human Services states, “Some studies suggest that populations who live near asbestos mines and mills have experienced excess asbestos-related diseases, specifically mesothelioma.”

Workers at the W.R. Grace vermiculite exfoliation plant were exposed to asbestos

The W.R. Grace plant was an exfoliation facility. That process required vermiculite to be heated to high temperatures. The water contained in the mineral converted to steam and then separated the mineral into its layers, expanding the vermiculite into small worm-shaped pieces. By doing this, its bulk volume was expanded, or “popped,” and the mineral became a commercially valuable product – primarily for attic insulation, concrete aggregate, masonry insulation, horticultural soil conditioner, and a spray-applied fireproofing. But, in this process, asbestos was released and made available for human exposure.

There was a population of 5,047 within one mile of the facility in 1989, the time production ceased. Jefferson Parish still ranks 19th among all U.S. counties in deaths from mesothelioma.

W.R. Grace reported that at the time operations ceased, a remediation was conducted at the site including vacuum and water rinse of equipment, walls, and floors, and removal of equipment.

What to do if you think you were exposed

Diseases from asbestos exposure, such as mesothelioma, can take up to 50 years before symptoms appear. It has only been 30 years since Libby vermiculite processing ceased. If you think you were exposed, the first precaution would be to stop smoking as that can aggravate any potential lung disease. It would also be prudent to let your doctor know the timeframe and degree of exposure you experienced and have regular checkups.

Exposure from working with a product containing asbestos, such as Libby vermiculite, dramatically increases the risk of disease. The sad truth is that those exposed to vermiculite had no idea they were inhaling fibers that would potentially shorten their lives.

Lafayette Natural Science Museum and Planetarium Demolition Delayed Because of Asbestos

By

The Lafayette Natural Science Museum and Planetarium demolition delayed because of asbestos, increased the time to tear it down from 72 days to a delay of seven months. It also added a 40 percent increase to the demolition contract, increasing it from $295,500 to $412,591.

Demolition delayed because of asbestos adds to history of the building

The building was constructed in 1969, a time when asbestos was widely used. However, by 2001 it had fallen into disrepair and was vacated in 2001. In the past 16 years, the place became a place for curiosity seekers and others who abused the abandoned structure.

By 2015, the City-Parish Council approved demolishing the building and replacing it with a green space for residents. Delays occurred in the years since as drainage improvements were added to the scope of work, followed by the asbestos discovery.

A lesson for all

This type of scenario is not unique to Lafayette, Louisiana as thousands of buildings across the country were built during the years asbestos was freely used in construction of government, commercial, and residential building.

This unfortunate surprise happened because the city’s engineering department assumed that there was no asbestos since the air-conditioning system was reported to be clear of the mineral. However, because the Louisiana Department of Environmental Quality required a DEQ permit that included an asbestos assessment before demolition, asbestos was discovered in the walls as a waterproofing material.

The lesson for anyone who intends to disturb a building built from the 1930s through the 1970s, is to check for asbestos before any work is begun. Proceeding without an inspection, and possibly abatement, can cost considerably more than expected in both money and the lives of those who may be exposed to the fibers.

There is no safe level of asbestos exposure and the result can include lung cancer, asbestosis, and the fatal disease malignant mesothelioma.